Inhibitory effect of Phyllanthus urinaria L. extract on the replication of lamivudine-resistant hepatitis B virus in vitro Jaesung Jung1,2, Nam Keun Kim3, Sun Park1,2, Ho-Joon Shin1,2, Seong Gyu Hwang3,4* and Kyongmin Kim1,2* Abstract Background: Long-term treatment of chronic hepatitis B (CHB) with nucleos(t)ide analogs results in the emergence Chemo/Radiation Side Effects Contact me Links Phyllanthus urinaria. References & Further Information [1] Nadkarmi KM. (1992) reported that seeds of P. urinaria require light for germination, and as such, seeds buried deeper than 5 cm failed to germinate. Chanca Piedra - Phyllanthus niruri Database file in the ... It should also be avoided in people with Wilson’s disease because it can further reduce uric acid levels and increase the risk of liver damage. The website also provides access to a database and images of herbarium specimens found at the University of South Florida and other herbaria. The oral administration of P. urinaria to mice caused significant inhibition of … Phyllanthus (Phyllanthus amarus) - Digital Naturopath Phyllanthus urinaria propagates principally through seeds. Phyllanthus urinaria Cancer Ther. urinaria is used in folk medicine as a cure to treat jaundice, diabetes, malaria, and liver diseases. Phyllanthus urinaria koreanis extract inhibits HBV DNA synthesis and the secretion of HBsAg and HBcAg.a Southern blot analysis to determine HBV DNA synthesis after treatment with LMV or Phyllanthus extract. Side effects tend to be mild and may include stomach upset and diarrhea. Due to the lack of research, Phyllanthus should be avoided in children, pregnant women, and nursing mothers. It should also be avoided in people with Wilson's disease as it may further reduce uric acid levels and increase the risk of liver damage. Phyllanthus require substrate temperatures above 75 oF to germinate and thus are more common in the summer, but will persist into late fall in the southeastern US (and year-round in sub-tropical areas). At 1 day post-transfection, HepG2 cells were treated with 50 or 100 μg/mL of Phyllanthus extract or LMV (4 μg/mL) for 48 h. HBV DNA was then … The current study is focused on screening of phytochemicals from Phyllanthus urinaria that has substantial anti-diabetic effects. Conventional treatment with interferon – alpha is very expensive and has many serious side effects. This report aimed to characterize the whole P. urinaria plant, present the anticancer effects of P. urinaria both in vivo and in vitro, and explore relevant mechanisms. 2.1.Plant collection: Leaves from Phyllanthus urinaria plant were collected from Sangli district in Maharashtra, India. Therefore, supplements which are natural and safe are increasingly used by both for health promotion and sport competition to reduce pain. Side effects are usually mild and may include abdominal pain and diarrhea. Anti-Tumor-Phyllanthus urinaria, a widely used herb medicine in Asia, was tested for its anti-tumor effect in vivo for the first time.The anti-tumor activity in P. urinaria extract was evaluated by its effect on tumor developed in C57BL/6J mice with implantation of Lewis lung carcinoma cells.. An aqueous extract obtained from the whole P. urinariaplant cause cytotoxic effects in various types of cancer cells by induction of DNA fragmentation and cell apoptosis along with increased caspase-3 activity and reduced telomerase activity (Huang et al., 2009, 2010). K562 cells and cancer cells from solid tumor origins had more tolerance to P. urinariaextract. extract decreased BGL by 23% and 39% at the doses of 10 and 30 mg/kg, respectively. Commonly used in healing in traditional Vietnamese and Chinese medicine, species such as Echinacea emblica, also known as forest tamarind, and Echinacea niruri, have long been considered a medicinal remedy. Wehtje et al. The mechanism seems to be that this is reached by decreasing inflammation. The mechanism seems to be that this is reached by decreasing inflammation. How Phyllanthus Amarus is effective for various diseases is listed in repertory format. Methods: Myers's method was used to evaluate the protection of intravenously administered PUW against the male mouse sudden death caused by injection of 75 mg/kg arachidonic acid in the tail vein; … The "urinaria" in its botanical name comes from its historical (and current) use to treat kidney and urinary stones. Chronic Hepatitis B. In preliminary research in animals, extracts of Phyllanthus plants have shown promising results in pain relief. Anti-Tumor-Phyllanthus urinaria, a widely used herb medicine in Asia, was tested for its anti-tumor effect in vivo for the first time.The anti-tumor activity in P. urinaria extract was evaluated by its effect on tumor developed in C57BL/6J mice with implantation of Lewis lung carcinoma cells.. There have been many investigations into its medicinal virtues and several active compounds have been found including lignans, ellagitannins, terpenoids, flavonoids, phenolic compounds and waxes [. ... significant side effects have not been reported. In a 2018 study, researchers found that Phyllanthus niruri has a diuretic effect in rats, boosting the excretion of sodium in the urine. Anti-Diabetes - Hypoglycemic effects of the extracts of two Siamese plants, Momordica charantia (M.c.) This review … Phyllanthus amarus, Phyllanthus niruri, Phyllanthus urinaria Principal Proposed Uses. Phyllanthus urinaria (P. urinaria), a widely used herbal medicine, has been reported to possess various biological activities. The preparation of cream is given bellow in steps. Extracts of Phyllanthus spp., including P. urinaria and P. niruri, were also shown to have significant anti-cancer activity ( Zuraihan, 2002 ). Fang SH, Rao YK, Tzeng YM. Antioxidative and cardioprotective effects of Phyllanthus urinaria L. on doxorubicin-induced cardiotoxicity Abstract Cardiac toxicity is a major adverse effect caused by doxorubicin (DOX) therapy. Alternative herbal medicine using extracts of Phyllanthus niruri and Phyllanthus urinaria have been reported to be effective against … It was also evident from the result this did not occur via the inhibition of … "Antimetastatic potentials of Phyllanthus urinaria L on A549 and Lewis lung carcinoma cells via repression of matrix-degrading proteases." 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